David and Karen
David and Karen were both identified as being carriers for cystic fibrosis. They decided to have preimplantation genetic testing (PGT-M), to ensure that they would not have a child affected by cystic fibrosis.
Davids's nephew was diagnosed with cystic fibrosis shortly after birth. This led to David and Ruth both being tested and they were both found to be carriers of the cystic fibrosis gene. As cystic fibrosis is an autosomal recessive genetic condition this meant that they had a one in four chance of their baby being affected by cystic fibrosis, and needing lifelong care.
They decided to have preimplantation genetic diagnosis (PGT-M) with the embryos being genetically tested for cystic fibrosis and other chromosomal abnormalities before they were replaced into Ruth.
"Being able to ensure that Harry didn't have cystic fibrosis was amazing, the whole team at GRFC was fantastic"