ICSI Intra-cytoplasmic sperm injection

When more complex barriers are keeping you from getting pregnant, advanced lab techniques can help.

ICSI may be recommended as part of an IVF procedure to treat many causes of infertility.

Also discover the various revolutionary advancements in treating male infertility cases.

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  • Introduction

    Intracytoplasmic sperm injection (ICSI) is performed as part of in the in vitro fertilization (IVF) procedure. It is a process in which an embryologist injects a single sperm into the cytoplasm (centre) of each egg and observes the egg over the next day or so. If fertilization occurs and the embryo matures properly, a doctor can transfer it into the uterus.

    In a normal ovulation cycle, one egg matures per month. The goal of an ICSI cycle is to have many mature eggs available to increase chances of success with treatment. This is achieved through stimulation of the ovaries.

  • Stimulation of the ovaries

    In the stimulation phase, injectable medications are used for approximately 8 to 14 days to stimulate the ovaries to produce eggs. During this phase, a patient will come into the clinic up to 8 times for morning monitoring and medication adjustment if needed.

  • Egg retrieval

    On the morning of egg retrieval, a patient will meet a doctor and an anaesthetist to review their medical history including sperm samples being used. Intravenous fluid will be administered to induce sleep. The egg retrieval itself takes about 20 to 30 minutes via ultrasound and removal of egg via a needle.

    The andrology laboratory will wash and prepare the sperm so the healthiest sperm are brought together with the eggs for fertilization (after the doctor performs the egg retrieval).

  • Fertilisation

    After the egg retrieval, the embryologist will prepare the eggs and sperm. For Pre-implantation genetic testing (PGD) the embryologist will inject one single sperm into each mature egg under a microscope. PGD is therefore possible with very few sperm.

  • Embryo development

    Embryo development begins after fertilization. An embryologist examines each developing embryo over the course of the following 5 to 6 days to see progressive development.

  • Embryo transfer

    The embryo transfer is a simple procedure that only takes about 5 minutes to complete. There is no anaesthesia or recovery time needed. A patient will review their cycle with the doctor and the number of embryos recommended for transfer. The nurse will give the patient instructions for the following 2 weeks until it's time for the pregnancy test.

  • The pregnancy test

    Two weeks after the embryo transfer, in the privacy of their own home, a patient will perform a pregnancy test and advises the outcome so Glasgow Royal Fertility Clinic can plan the next steps.


Our full price list can be found here for download. Should you have any questions about the fees, please contact us on 0141 956 0509 and speak to a member of staff.